Peninsula Avenue Veterinary Clinic Blog

We have been open the regular hours of 9am-6pm Monday through Friday and 8:30am to 12:30pm Saturdays. We are following the CDC and San Mateo County Health Dept policies very strictly. Only patients are allowed inside the hospital. We all wear masks and keep 6 feet distance. We have no sick employees come to work and ask that clients let us know if have signs or tested positive for COVID-19. We want to be able to stay open for our patients without interruption.

0 Comments

Curbside service and Hospital Hours

5/5/2020

0 Comments

Curbside Service is working well to keep our physical distancing while taking care of our patients. Thank You for your cooperation. We have restarted our Saturday hours last week. So we are currently open Monday through Friday 9am to 5pm and Saturdays 8:30am to 12:30pm. We have some staff working answering phones and emails from home right now to keep us all as safe as possible. Hope this situation changes soon and that our families and friends fare well during these very unusual times. We will keep you posted of any other schedule changes.

0 Comments

USDA Statement on the Confirmation of COVID-19 in a Tiger in New York

4/6/2020

0 Comments

USDA Statement on the Confirmation of COVID-19 in a Tiger in New York
Last Modified: Apr 6, 2020
Contact:
APHISpress@usda.gov
(Washington, D.C. April 5, 2020) – The United States Department of Agriculture’s (USDA) National Veterinary Services Laboratories has confirmed SARS-CoV-2 (the virus that causes COVID-19 in humans) in one tiger at a zoo in New York. This is the first instance of a tiger being infected with COVID-19. Samples from this tiger were taken and tested after several lions and tigers at the zoo showed symptoms of respiratory illness.
Public health officials believe these large cats became sick after being exposed to a zoo employee who was actively shedding virus. The zoo has been closed to the public since mid-March, and the first tiger began showing signs of sickness on March 27. All of these large cats are expected to recover. There is no evidence that other animals in other areas of the zoo are showing symptoms.
USDA and CDC are monitoring the situation and working to support the state and local health departments and state animal health officials. State animal and public health officials will take the lead in making determinations about whether animals, either at this zoo or in other areas, should be tested for the SARS-CoV-2 virus. USDA will notify the World Organisation for Animal Health (OIE) of this finding.
Anyone sick with COVID-19 should restrict contact with animals, out of an abundance of caution including pets, during their illness, just as they would with other people. Although there have not been reports of pets becoming sick with COVID-19 in the United States, it is still recommended that people sick with COVID-19 limit contact with animals until more information is known about the virus. If a sick person must care for a pet or be around animals, they should wash their hands before and after the interaction.
Questions and Answers:
Can people give this virus to animals and, if so, what animals are at risk?
This is the first case of its kind. We are still learning about this new coronavirus and how it spreads. This case suggests that a zoo employee spread the virus to the tiger. Further studies are needed to understand if and how different animals could be affected by COVID-19. State animal and public health officials will continue to work closely with USDA and CDC to monitor this situation and will conduct additional testing if it is warranted.
If multiple animals were showing symptoms, why was only one tested?
Only one tiger was tested as the collection of diagnostic samples in big cats requires general anesthesia. Since all tigers and lions were exhibiting similar respiratory symptoms, the attending veterinarian felt it was in the best interest of the animals to limit the potential risks of general anesthesia to one tiger for diagnostics.
If animals can catch the virus, can they give it back to people?
At this time, there is no evidence to suggest that any animals, including pets or livestock, can spread COVID-19 infection to people.
Will this finding prompt additional testing of animals?
No. This is an evolving situation, however, routine testing of zoo or personal animals is not recommended at this time. Public and animal health officials may decide to test certain animals that are showing signs of illness and that are known to have been exposed to the virus. More information about how those decisions will be made is available here: https://www.aphis.usda.gov/…/faq-public-on-companion-animal…
Should any animal showing signs of respiratory illness be tested?
USDA and CDC do not recommend routine testing of animals for this virus. Because the situation is ever-evolving, public and animal health officials may decide to test certain animals out of an abundance of caution. The decision to test will be made collaboratively between local, state or federal public and animal health officials.
Should I avoid contact with pets or other animals if I am sick from coronavirus (COVID-19)?
You should restrict contact with pets and other animals while you are sick with COVID-19, just like you would with other people. Although there have not been reports of pets becoming sick with COVID-19 in the United States, it is still recommended that people sick with COVID-19 limit contact with animals until more information is known about the virus. When possible, have another member of your household care for your animals while you are sick. If you are sick with COVID-19, avoid contact with your pet, including petting, snuggling, being kissed or licked, and sharing food. If you must care for your pet or be around animals while you are sick, wash your hands before and after you interact with pets. More information is available on how to keep people and animals safe at https://www.cdc.gov/…/2019-n…/daily-life-coping/animals.html.
What should I do if I think my animal has the virus?
Call your veterinary clinic with any questions about your animal’s health. In order to ensure the veterinary clinic is prepared for the household animal, the owner should call ahead and arrange the hospital or clinic visit. Make sure to tell your veterinarian if your animal was exposed a person sick with COVID-19, and if your animal is showing any signs of illness. Veterinarians who believe an animal should be tested will contact state animal health officials, who will work with public and animal health authorities to decide whether samples should be collected and tested.
Could this affect tigers or other animals at other zoos across the United States?
There is no evidence of this virus affecting animals at any other facilities in the United States. However, anyone sick with COVID-19 should restrict contact with animals, including pets, during their illness, just as they would with other people. Although there have not been reports of pets becoming sick with COVID-19 in the United States, it is still recommended that people sick with COVID-19 limit contact with animals until more information is known about the virus. If a sick person must care for a pet or be around animals, they should wash their hands before and after the interaction.

0 Comments

SARS-CoV-2 and domestic pets

4/6/2020

1 Comment

Excerpts from Coronaviruses in the domestic animal kingdomWhat the zoonotic origin of SARS-CoV-2 implies for pets and livestock
April 3, 2020 (published)
By Natalie Slivinski

Since February, four household pets have tested positive for SARS-CoV-2, the coronavirus sweeping the globe: two dogs in Hong Kong, a Pomeranian and a German shepherd; a cat in Belgium; and, most recently, a cat in Hong Kong. All the animals' owners had COVID-19. Although they apparently picked up viral particles shed by their human companions, none of the Hong Kong pets showed signs of illness consistent with COVID-19. The Belgian cat, however, did become sick, showing signs about a week after its owner became ill.
The occurrences raise questions about whether pets could become part of the COVID-19 transmission chain. Veterinarians and other health experts say there is no cause for owners to abandon their animals for fear of catching the disease — if anything, it's the pets who should be kicking us out. There is no evidence that pets can transmit the virus back to people. "I think it's far more likely that they'll get it from the person that's shedding large amounts of virus, rather than the other way around," said Dr. Melissa Kennedy, a virologist at the University of Tennessee College of Veterinary Medicine.
Medical experts say the real threat lies in human-to-human transmission. While some pet species may be able to pick up infections, that doesn't mean they play a role in spreading the virus. Still, research is ongoing, and owners should include their pets when practicing COVID-19 precautions.
In his blog Worms & Germs, Dr. J. Scott Weese, a pathobiologist and internal medicine specialist at the University of Guelph's Ontario Veterinary College, advises: "If you're sick, stay away from animals just like you would other people. If you have COVID-19 and have been around your pets, keep your pets inside and away from other people. While the risk of transmission to or from a pet is low, we don't want an exposed pet tracking this virus out of the household (just like we don't want an infected person doing that)."
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
The veterinary and research communities remain vigilant. But although domestic animals such as cats and dogs may be infected, viral transmission in household pets is considered unlikely. Based on current evidence, Kennedy believes that dogs are not "epidemiologically important" for COVID-19. That's because there's more to a successful infection than sticking to host cells. And while humans provide a very comfortable environment for SARS-CoV-2, Kennedy said, dogs apparently do not.
'Infected' versus 'infectious'
The dogs that tested positive in Hong Kong were found to have viral RNA in the mouth and nose. When the Hong Kong Agriculture, Fisheries and Conservation Department performed serological tests to measure antibodies against COVID-19 in the blood of the Pomeranian, the final result came back positive, indicating a bona fide infection. However, the dog never showed any clinical signs.
In fact, you can be infected with a virus without feeling sick. When you feel ill, it's the result of the virus replicating to high enough levels to do two things: first, to destroy large numbers of healthy cells; and second, to trigger inflammation that can cause unpleasant symptoms such as fever and coughing. But if the virus can't replicate efficiently, it can't muster enough copies of itself to pose much of a challenge to the body's immune system, which mounts a coordinated attack and clears out the invader before its host notices symptoms.
It seems likely, Kennedy said, that dogs are not a hospitable host for SARS-CoV-2. "The host specificity of a virus is determined, basically, by two factors," she explained: "One, that the cells the virus is infecting have a receptor that it can attach to. And then, once the virus is inside the cell, that cell has to be able to provide everything that the virus needs in order to replicate."
While dogs' cells might have a fitting ACE2 receptor, Kennedy suspects that SARS-CoV-2 isn't happy enough in the canine cellular environment to replicate to high levels. There must also be a large enough dose of virus to breach the frontline defenses of every new host. Without the ability to replicate efficiently, the virus has nowhere to go.
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
In humans, there's no doubt: Our bodies are like a five-star hotel for SARS-CoV-2. We can transmit the disease even without symptoms, perhaps because our cells are quite permissive to the virus. This effect is amplified in cities, where the high density of people means that a large population is being exposed to particularly high levels of virus.
As for dogs, Kennedy believes they are likely a dead end for SARS-CoV-2 — meaning they can catch the virus but they cannot give it back. While human cells are permissive for some reason, canine cells may not be. "From what we know thus far, the dog is not providing everything that virus needs in order to replicate to significant enough levels to make it important in the spread of the virus," she said. "There may not be enough permissive cells. But that's under investigation now."
The cells of cats and ferrets, however, appear to be more receptive to coronaviruses. Scientists at Harbin Veterinary Research Institute in China, in a study not yet peer reviewed, found that "SARS-CoV-2 replicates poorly in dogs, pigs, chickens and ducks, but efficiently in ferrets and cats. We found that the virus transmits in cats via respiratory droplets."
The finding on cats and ferrets is consistent with the SARS virus from 2002. For that reason, Weese, who is a zoonotic disease expert at Ontario Veterinary College, anticipated some weeks ago that cats and ferrets might become infected by the virus that causes COVID-19. "With the original SARS virus, cats ... were able to grow enough virus to pass it on to another cat," he said.
Weese was therefore unsurprised by the news about the Belgian cat, which had both a positive test result and clinical signs. According to an article in The Brussels Times, the cat had diarrhea, vomiting and difficulty breathing. Researchers found virus in the cat's feces, the newspaper reported. The cat in Hong Kong, which has not shown any signs of the disease, also had virus in its rectal samples, as well as in its mouth and nose, according to the government statement.
Ferrets, too, have been found to have ACE2 receptors and are permissive to a number of viruses that infect humans, including some types of bird flu and seasonal flu, according to Kennedy. Early studies have shown that SARS-CoV-2 replicates well in ferret cells. However, Weese believes their transmission risks are low, at least from an epidemiological standpoint.
"If you put a cat and a ferret in front of me and ask me which one I want to get in close contact with, I'd pick the cat, because ferrets are high risk at that one-on-one level," he said. "But for me, cats are still a bigger concern because there are a lot more cats than ferrets."
While the susceptibility of ferrets may be worrisome for ferret owners, it could be a boon for COVID-19 research. According to the New York Times, scientists at the University of Pittsburgh recently found that a ferret in their lab developed a high fever after being exposed to SARS-CoV-2. The strong immune response suggests ferrets likely are vulnerable to illness, which makes them a promising animal model for developing a COVID-19 vaccine.
Assessing risk
Despite the ferret finding, experts believe the likelihood of catching COVID-19 from a pet ferret or cat is low. Even if transmission to individual owners is theoretically possible, both Weese and Kennedy believe the risk does not translate to large-scale spread.
"An infected cat isn't a big concern in the household, since the person who exposed the cat in the first place is the main risk," Weese wrote last week in his blog. "The virus is being transmitted very effectively person to person, so animals likely play little role, if any, in the grand scheme of things."
Other than the Belgian cat, there are no other reports of domestic animals, including livestock, getting sick with COVID-19. That could change, of course; more animals from households with COVID-19 cases need to be tested to form a clearer picture.
Furthermore, coronaviruses constantly mutate. They are RNA viruses, which, unlike DNA viruses, have no proofreading enzymes that fix mistakes in the course of replicating. Coronaviruses also have unusually large genomes. That leads to a large number of mutations, and such genetic "mistakes" are what drive their evolution. "Those mistakes are purely random," Kennedy explained, "but if they give that virus selective advantage over its comrades, then that mutation will be maintained in the virus population."
If SARS-CoV-2 were to mutate such that the virus became more able to infect and spread, domestic animals could become reservoirs. That would have major implications for a world full of pet and livestock owners. It's also theoretically possible the virus could find a way to spill over from cats or ferrets back into humans. But there's no evidence to date that this is happening.
A call for common sense
Weese is working on testing more animals from COVID-19-positive households. "We're trying to do active surveillance of animals that are in contact with infected people," he said.
If many more positive tests emerge in pets, public-health experts will review the transmission risks. But routinely testing large populations of domestic animals would be impractical and probably not very informative, Weese said: "Testing is useful to use from a research standpoint, but testing your average animal isn't something we want to get done."
His focus is on practical protective measures. For pig farmers, for example, simply exercising caution may effectively prevent transmission. "If you've got COVID and you've got pigs but you don't go near the barn, then we don't have to worry about it," Weese said. "And with farmers, it's actually probably easier [than with pet owners], because a pig farmer realizes that if someone reports a pig being positive, pork prices are going to plummet."
For pet owners, it's about managing animals the same way we manage people, Weese said. This means staying separated from pets if you're sick, as painful as it may be to deny yourself snuggle therapy. It also means including pets in social distancing. If you are under local stay-at-home orders and keeping a distance from others, keep your pet distant from others, too. Even if pets can't get COVID-19, viral particles can get on their mouth, nose, fur or skin and be picked up by the next person who touches them. Think of pets as another surface that can be contaminated, like a countertop or door handle. The overall message, Weese said, is simple: "Just use common sense."
The best defense against transmission by household pets is to keep exposed animals in the home but sometimes this is impossible; for instance, if someone who lives alone needs to be hospitalized. In a blog post Thursday, Weese discusses options for such situations. The best scenario, he writes, is for someone who has recovered from COVID-19 to come into the household to continue caring for the pet. If no one is available, not even a benevolent low-risk neighbor, owners may be able to temporarily house their pet with a shelter or clinic that has the facilities and capacity. Weese's own hospital is positioned to house animals from COVID-19 households. Space is limited, and the option is intended as a last resort. "We're set up to handle those animals," he said, "but our focus is to keep animals in the household or find alternative approaches rather than see them in clinics."

1 Comment